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KMID : 0383820080650030183
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Tuberculosis and Respiratory Diseases
2008 Volume.65 No. 3 p.183 ~ p.190
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Health-related Quality of Life Measurement with St. George`s Respiratory Questionnaire in Post-tuberculous Destroyed Lung
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Lee Byoung-Hoon
Kim Young-Sam
Lee Ki-Deok
Lee Jae-Hyung
Kim Sang-Hoon
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Abstract
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Background: The control of active pulmonary tuberculosis is still an issue in community medicine. But there are
also considerable needs for supportive management of symptomatic patients with post-tuberculous destroyed lung.
Few studies have evaluated clinical characteristics and health-related quality of life in patients with post-tuberculous
destroyed lung.
Methods: We evaluated lung function, exercise tolerance, HRCT and health-related quality of life measurements
using the Korean version of St. George’s Respiratory Questionnaire (SGRQ) in 22 patients with parenchymal damage
to more than a half of one lung due to pulmonary tuberculosis.
Results: In the pulmonary function test, mixed defects and obstructive defects were observed in 10 (45.0%) and 9
(40.9%) of patients, respectively. In the cardiopulmonary exercise test, the mean VO2max% predicted (39.0%±10.9%)
and O2 pulse% predicted (61.3%±13.6%) were markedly decreased. In the SGRQ, the impact score (mean 27.8±18.5)
was significantly lower than the symptom score (mean 53.9±20.9) or activity score (mean 50.8±27.3) (p＜0.05,
p＜0.01). Cronbach’s alpha coefficient value for reliability was more than 0.7 for each subscale and total score.
The total score showed a significant negative correlation with FEV1% predicted (r=?0.46, p＜0.05) and SaO2 (r=?
0.60, p＜0.05). On HRCT, a median of 9 (range 5∼15) bronchopulmonary segments were destroyed by less than
half, which significantly correlated with SGRQ total score (r=?0.52, p=0.02).
Conclusion: The reliability and validity of the Korean version of the SGRQ was acceptable for the measurement
of health-related quality of life in patients with post-tuberculous destroyed lung.
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KEYWORD
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Tuberculosis, Quality of Life, Pulmonary function test
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